We develop new biophysical methods to understand how molecular machines edit and repair our genomes. Current lab interests include CRISPR-cas adaptive immunity and eukaryotic DNA repair.

News

February 8, 2024: Dr. John Cooper defends his PhD! Congrats!

November 29, 2023: Dr. Hung-Che (Jami) Kuo defends his PhD! Congrats!

November 17, 2023: Dr. Kuang Hu defends his PhD! Congrats!

November 13, 2023: Joe Woodman and Da Huo join the Finkelstein lab as rotation students!

August 31, 2023: Dr. Andrea Quezada departs the lab to work at Max Delbrück Center in Berlin, Germany! Congratulations!

Recent Papers
High-speed AFM imaging reveals DNA capture and loop extrusion dynamics by cohesin-NIPBL

Kaur et al.

Published 28 Sep 2023
Asgard archaea defense systems and their roles in the origin of immunity in eukaryotes

Leão et al. BioRxiv (2023)

Published 13 Sep 2023
CTCF and R-loops are boundaries of cohesin-mediated DNA looping

Zhang et al. Mol. Cell (2022)

Published 17 Aug 2023
Unraveling the mechanisms of PAMless DNA interrogation by SpRY Cas9

Hibshman et al. BioRxiv (2023)

Published 22 Jun 2023